Structure of PDB 7zi4 Chain H

Receptor sequence
>7zi4H (length=412) Species: 9606 (Homo sapiens) [Search protein sequence]
PFRDARAAPDPVLEAGPVAHGPLPVPLVLDNGSFQVRAGWACPGQDPGPE
PRLQFRAVCARGRGGARGASGPQMLRSPFDRNVPVNLELQELLLDYSFQH
LGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLF
SFYHNKPKNSMCSGLIISSGYQCTHVLPILEGRLDAKNCKRINLGGSQAA
GYLQRLLQLKYPGHLAAITLSRMEEILHEHSYIAEDYVEELHKWRCPDYY
ENNVHKMQLPFSVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAE
TLQYILDRYPKDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRSS
FQVQLASNPVLDAWYGARDWALNHLDDNEVWITRKEYEEKGGEYLKEHCA
SNIYVPIRLPKQ
3D structure
PDB7zi4 Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
ChainH
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP H F40 G189 Y190 G215 H247 G496 M499 F34 G170 Y171 G196 H228 G326 M329
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0000723 telomere maintenance
GO:0006275 regulation of DNA replication
GO:0006281 DNA repair
GO:0006282 regulation of DNA repair
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0033044 regulation of chromosome organization
GO:0045739 positive regulation of DNA repair
GO:0045893 positive regulation of DNA-templated transcription
GO:0045995 regulation of embryonic development
GO:0051726 regulation of cell cycle
GO:0060382 regulation of DNA strand elongation
GO:0070914 UV-damage excision repair
GO:1904507 positive regulation of telomere maintenance in response to DNA damage
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0031011 Ino80 complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7zi4, PDBe:7zi4, PDBj:7zi4
PDBsum7zi4
PubMed
UniProtQ9H9F9|ARP5_HUMAN Actin-related protein 5 (Gene Name=ACTR5)

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