Structure of PDB 7yhs Chain H

Receptor sequence

>7yhsH (length=325) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]

LSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISN
RLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGT
PSACNDAAYRDKLLQTVATYVNEQGFAELARRYAHNLANARFLWRNRVGA
EAVEVRINHIRQGEVARTWRFDALAIGLRDFKADAELDALAELIASGLSG
SGHVLLEVVAFARIGDGQEVFPSQELILKSKTLYSVRDAAAIHSQKIGNA
LRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVL
RDEAPAVEQQHYVIANLIRGGVFGE

3D structure

PDB

7yhs Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage.

Chain

Resolution

3.37 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	A32 F33 E34 R35 V68 R69 W168 R169 Q248 L250 N281 R284 R351 G352 G353 V354	A8 F9 E10 R11 V44 R45 W144 R145 Q224 L226 N249 R252 R319 G320 G321 V322
BS02	dna	H	S29 V30 P93 N94 L95 Q96 E357	S5 V6 P69 N70 L71 Q72 E325

External links

PDB	RCSB:7yhs, PDBe:7yhs, PDBj:7yhs
PDBsum	7yhs
PubMed	36209819

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