Structure of PDB 7xye Chain H

Receptor sequence
>7xyeH (length=479) Species: 285500 (Streptomyces luteocolor) [Search protein sequence]
VIVVGNGVLGLSVGVEIARTRPDVRVTLLGKPARQYGATPAAGAMLGAFG
EVTAHALASEHGRKKHALAVQAQRLWPEWIESLEATGTAADGRIKTADDT
VVLLNTVGHSALDDANFAAVLTALKEANAPHEEIAVESVDWIDPDPNSRP
LRALHIEGEGSVDSGILLAALERSFLQAGGRLHPVDATEIRASHGRVEGV
VTDDGDFLPAGHVVVAAGARSQRLVAALPGLAHRIPRIYDGVGVSALVDT
WDGSGPATVLRTSNRAFACGLHLVPRAGGSVYIGATNAVCLEPRGAASIE
ETVFLFNCATHQLHRGLNGSELRKVQVGSRPAPIDGFPLIGGTSVEGLWM
LSGTYRDGLHMSPLLARHVVSLMDGGTGVDGLREFRPERDLISAWSREEI
LDDVVRHTMATGYEFPWRLPLEWPHMMETFLQGPFAELADRLSDTYTPPA
DLMTAIMFSEREQQDELIAYYADVHREWH
3D structure
PDB7xye N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
ChainH
Resolution2.482 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD H G17 N18 G19 L21 G42 R46 Q47 A50 T51 A53 A54 M57 D198 A199 G230 R232 Y294 G340 R342 T366 Y367 R368 D369 G370 L371 H372 G5 N6 G7 L9 G30 R34 Q35 A38 T39 A41 A42 M45 D186 A187 G218 R220 Y282 G328 R330 T354 Y355 R356 D357 G358 L359 H360
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:7xye, PDBe:7xye, PDBj:7xye
PDBsum7xye
PubMed37137912
UniProtA0A125SZC1

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