Structure of PDB 7xuz Chain H

Receptor sequence
>7xuzH (length=90) Species: 9606 (Homo sapiens) [Search protein sequence]
GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKK
3D structure
PDB7xuz Structural insights into transcription regulation by the higher-order HDAC4-MEF2-DNA complex
ChainH
Resolution3.591 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H G2 R3 T20 K23 R24 K30 G1 R2 T19 K22 R23 K29
BS02 dna H G2 R3 K4 K5 K31 G1 R2 K3 K4 K30
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:7xuz, PDBe:7xuz, PDBj:7xuz
PDBsum7xuz
PubMed38281192
UniProtQ02078|MEF2A_HUMAN Myocyte-specific enhancer factor 2A (Gene Name=MEF2A)

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