Structure of PDB 7x75 Chain H

Receptor sequence
>7x75H (length=131) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence]
PPVKGRATRQRAAVSAALQEVEEFRSAQELHDMLKHKGDAVGLTTVYRTL
QSLADAGEVDVLRTAEGESVYRRCSTGDHHHHLVCRACGKAVEVEGPAVE
KWAEAIAAEHGYVNVAHTVEIFGTCADCAGA
3D structure
PDB7x75 Structural basis of Streptomyces transcription activation by zinc uptake regulator.
ChainH
Resolution3.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H R11 A12 Q33 Y52 E73 R6 A7 Q28 Y47 E68
BS02 dna H Q15 R16 V46 G47 T49 T50 R53 Q10 R11 V41 G42 T44 T45 R48
BS03 ZN H C90 C93 C130 C85 C88 C125
BS04 ZN H D65 C79 H85 H87 D60 C74 H80 H82
BS05 ZN H H84 H86 H122 H79 H81 H117
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:1900376 regulation of secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0032993 protein-DNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7x75, PDBe:7x75, PDBj:7x75
PDBsum7x75
PubMed35871291
UniProtQ9L2H5

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