Structure of PDB 7um3 Chain H

Receptor sequence

>7um3H (length=214) Species: 9606 (Homo sapiens) [Search protein sequence]

VQLQQWGAGLLKPSETLSLTCAVYGFSDYYWNWIRQPPGKGLEWIGEINH
NGNTNSNPSLKSRVTLSLDTSKNQFSLKLRSVTAADTAVYYCAFGYSDYE
YNWFDPWGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVT
VSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHK
PSNTKVDKRVEPKS

3D structure

PDB

7um3 Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab.

Chain

Resolution

2.3983 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	Y33 S97 W100C	Y30 S97 W103

External links

PDB	RCSB:7um3, PDBe:7um3, PDBj:7um3
PDBsum	7um3
PubMed	35981087

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