Structure of PDB 7rpk Chain H

Receptor sequence
>7rpkH (length=151) Species: 10090 (Mus musculus) [Search protein sequence]
KLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFK
DEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEE
SLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKA
E
3D structure
PDB7rpk Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
ChainH
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA H K88 D89 E90 E91 D96 T126 E127 K50 D51 E52 E53 D58 T88 E89
BS02 CA H E90 E91 E127 D130 D132 H134 E52 E53 E89 D92 D94 H96
BS03 ZN H H141 D148 H183 H103 D110 H145
Gene Ontology
Biological Process
GO:0007267 cell-cell signaling
GO:0007275 multicellular organism development

View graph for
Biological Process
External links
PDB RCSB:7rpk, PDBe:7rpk, PDBj:7rpk
PDBsum7rpk
PubMed34707294
UniProtQ62226|SHH_MOUSE Sonic hedgehog protein (Gene Name=Shh)

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