Structure of PDB 7r3b Chain H

Receptor sequence
>7r3bH (length=364) Species: 1590 (Lactiplantibacillus plantarum) [Search protein sequence]
ERHLFTSESVSEGHPDKIADQISDAILDAMLAQDPQARVAVETSVTTGLV
LVFGEVSTKAYVDIQKVVRDTIKSIGYVDGQYGFDGDNCAVLVSLDEQGD
QGMMFGYAINETPELMPLPIALSHRLMRKIAALRKDGTIKWLRPDAKAQV
TVEYDEDNQPKRIDTVVLSTQHDPDVDLDTIRQTVIDQVIKAVLPADLLD
DQTKYLVNPTGRFVIGGPQGDAGLTGRKVIVDTYGGFAHHGGGAFSGKDA
TKVDRSASYAARYIAKNVVAAGLADQVEVQLAYAIGVAEPVSIAVDTAGT
GKVSDEALINAIRENFDLRPAGIIKMLDLQRPIYRQTAAYGHFGRTDIDL
PWEHTDKVDALKAA
3D structure
PDB7r3b Evolution of homo-oligomerization of methionine S-adenosyltransferases is replete with structure-function constrains.
ChainH
Resolution2.82 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.5.1.6: methionine adenosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM H H16 K176 G249 D250 H14 K147 G220 D221
BS02 PHE H L302 L390 A393 L273 L361 A364
BS03 PPK H H16 D18 R256 K257 H14 D16 R227 K228
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004478 methionine adenosyltransferase activity
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006556 S-adenosylmethionine biosynthetic process
GO:0006730 one-carbon metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7r3b, PDBe:7r3b, PDBj:7r3b
PDBsum7r3b
PubMed35762725
UniProtQ88XB8|METK_LACPL S-adenosylmethionine synthase (Gene Name=metK)

[Back to BioLiP]