Structure of PDB 7qo4 Chain H

Receptor sequence
>7qo4H (length=391) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
AAPYAAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSHLWDIMGDRQRL
GEEHPLQVARCTKIIKGKYVINLKQIAKFVVGLGERVSPTDIEEGMRVGV
DRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVE
LPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIG
SELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDDGAGGD
NEVQRTMLELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVE
FSLPDLEGRANIFRIHSKSMSVERGIRWELISRLCPNSTGAELRSVCTEA
GMFAIRARRKVATEKDFLKAVDKVISGYKKFSSTSRYMQYN
3D structure
PDB7qo4 Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
ChainH
Resolution7.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP H G212 P252 G253 T254 G255 K256 T257 N356 G136 P176 G177 T178 G179 K180 T181 N280
BS02 MG H E310 N356 E234 N280
BS03 ATP H R367 R370 R291 R294
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0031625 ubiquitin protein ligase binding
GO:0036402 proteasome-activating activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045732 positive regulation of protein catabolic process
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0070682 proteasome regulatory particle assembly
GO:1901800 positive regulation of proteasomal protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008540 proteasome regulatory particle, base subcomplex

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Molecular Function
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Cellular Component
External links
PDB RCSB:7qo4, PDBe:7qo4, PDBj:7qo4
PDBsum7qo4
PubMed
UniProtP33299|PRS7_YEAST 26S proteasome regulatory subunit 7 homolog (Gene Name=RPT1)

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