Structure of PDB 7nyc Chain H

Receptor sequence
>7nycH (length=404) Species: 9606 (Homo sapiens) [Search protein sequence]
SHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGDRRQC
VPTEPCEDAEDDCGNDFQCSTGRCIKMRLRCNGDNDCGDFSDEDDCESEP
RPPCRDRVVEESELARTAGYGINILGMDPLSTPFDNEFYNGLCNRDRDGN
TLTYYRRPWNVASLIYETKGEKNFRTEHYEEQIEAFKLSYSSKKEKMFLH
VKGEIHLGRFVMRNRDVVLTTTFVDDIKALPTTYEKGEYFAFLETYGTHY
SSSGSLGGLYELIYVLDKASMKRKAVNITSENLIDDVVSLIRGGTRKYAF
ELKEKLLRGTVIDVTDFVNWASSINDAPVLISQKLSPIYNLVPVKMKNAH
LKKQNLERAIEDYINEFSVRKCHTCQNGGTVILMDGKCLCACPFKFEGIA
CEIS
3D structure
PDB7nyc Structural basis of soluble membrane attack complex packaging for clearance.
ChainH
Resolution3.54 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA H L96 R97 N99 D101 D103 E110 L79 R80 N82 D84 D86 E93
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0001906 cell killing
GO:0006955 immune response
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0031640 killing of cells of another organism
GO:0050778 positive regulation of immune response
GO:0051260 protein homooligomerization
Cellular Component
GO:0005576 extracellular region
GO:0005579 membrane attack complex
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0044218 other organism cell membrane
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7nyc, PDBe:7nyc, PDBj:7nyc
PDBsum7nyc
PubMed34667172
UniProtP02748|CO9_HUMAN Complement component C9 (Gene Name=C9)

[Back to BioLiP]