Structure of PDB 7n2q Chain H

Receptor sequence
>7n2qH (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQISKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB7n2q Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
ChainH
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide H Y7 H9 T24 E45 R62 E63 I66 S67 D77 Y99 D116 Y123 T143 W147 Q155 L156 Y159 W167 Y171 Y7 H9 T24 E45 R62 E63 I66 S67 D77 Y99 D116 Y123 T143 W147 Q155 L156 Y159 W167 Y171
Gene Ontology
Biological Process
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
Cellular Component
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0042612 MHC class I protein complex
GO:0098553 lumenal side of endoplasmic reticulum membrane

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7n2q, PDBe:7n2q, PDBj:7n2q
PDBsum7n2q
PubMed36477533
UniProtA3F718

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