Structure of PDB 7lz4 Chain H

Receptor sequence
>7lz4H (length=268) Species: 9913 (Bos taurus) [Search protein sequence]
ASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA
GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTP
RADTVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLD
KWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENE
EFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLG
PCSDILKRNIQQYNSFVS
3D structure
PDB7lz4 Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations.
ChainH
Resolution4.155 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP H F198 G199 L201 R209 D211 W260 F90 G91 L93 R101 D103 W152
BS02 CMP H V281 V300 V313 F322 G323 E324 I325 R333 A335 V337 Y371 V173 V192 V205 F214 G215 E216 I217 R225 A227 V229 Y263
Gene Ontology
Molecular Function
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7lz4, PDBe:7lz4, PDBj:7lz4
PDBsum7lz4
PubMed34006641
UniProtP00514|KAP0_BOVIN cAMP-dependent protein kinase type I-alpha regulatory subunit (Gene Name=PRKAR1A)

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