Structure of PDB 7kd6 Chain H
Receptor sequence
>7kd6H (length=47) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFRGIVEQCCHSICSLEQLENYCN
3D structure
PDB
7kd6
Single-chain insulin analogs threaded by the insulin receptor alpha CT domain.
Chain
H
Resolution
2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
H
G8 V12 L15 F24 F25 R36 G37 I38 V39 N54 Y55 C56
G8 V12 L15 F24 F25 R26 G27 I28 V29 N44 Y45 C46
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:7kd6
,
PDBe:7kd6
,
PDBj:7kd6
PDBsum
7kd6
PubMed
36181268
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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