Structure of PDB 7d0i Chain H

Receptor sequence
>7d0iH (length=424) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
WANVENLDSFLQQVYTYYTGKGLSCIIVHRLFQILTVSFVIGFTTFITSP
ITYLVLWLFLSFLLALWIYYLTDIPRLWQMREFYIHALKIATADMPTVSW
QRVLYRLLKLKKRLDAYAIANRIMRKDNYFIALINNGIINIELPLLHRRI
LTHTTEWNINWCIFNFVFDEQGQLRSAFRNPNSRKRLSEELRRRFIVAGF
LNCLFAPIVAIYLVIHNFFRYFNEYHKNPGALSTRRYTPLALWTFREYNE
LQHFFDERINDSYAAASHYVSQFPDFNMIRLFKYISFILGSFTAILVIIT
VFDPSVLFYLGLFGSLIAVSRSIIPDETLVFAPEKALRRVITFTHYMPGW
WSDNMHSKAVQQEFCSLYSYRIVNLLWEILGILLTPVLLFFTFPSCSQDI
VDFFREHTINVEGVGYVCSYAVFQ
3D structure
PDB7d0i Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion.
ChainH
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LMN H F264 D347 E376 W377 N378 N380 F425 V429 W463 Q472 F62 D127 E156 W157 N158 N160 F205 V209 W243 Q252
BS02 LMN H Q209 Y271 H373 W377 Y432 E610 Q33 Y69 H153 W157 Y212 E378
Gene Ontology
Molecular Function
GO:0017128 phospholipid scramblase activity
Biological Process
GO:0000045 autophagosome assembly
GO:0000422 autophagy of mitochondrion
GO:0006869 lipid transport
GO:0006914 autophagy
GO:0009056 catabolic process
GO:0016236 macroautophagy
GO:0017121 plasma membrane phospholipid scrambling
GO:0034497 protein localization to phagophore assembly site
GO:0034727 piecemeal microautophagy of the nucleus
GO:0061709 reticulophagy
Cellular Component
GO:0000139 Golgi membrane
GO:0000329 fungal-type vacuole membrane
GO:0000407 phagophore assembly site
GO:0005776 autophagosome
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0034045 phagophore assembly site membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7d0i, PDBe:7d0i, PDBj:7d0i
PDBsum7d0i
PubMed33106658
UniProtO74312|ATG9_SCHPO Autophagy-related protein 9 (Gene Name=atg9)

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