Structure of PDB 6y5e Chain H

Receptor sequence
>6y5eH (length=94) Species: 9606 (Homo sapiens) [Search protein sequence]
RSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA
3D structure
PDB6y5e Structural mechanism of cGAS inhibition by the nucleosome.
ChainH
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H R32 R34 K35 Y41 R1 R3 K4 Y10
BS02 dna H S33 R34 Y43 S57 R87 S88 T89 S2 R3 Y12 S26 R56 S57 T58
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6y5e, PDBe:6y5e, PDBj:6y5e
PDBsum6y5e
PubMed32911482
UniProtO60814|H2B1K_HUMAN Histone H2B type 1-K (Gene Name=H2BC12)

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