Structure of PDB 6xjw Chain H

Receptor sequence

>6xjwH (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]

SEVQLVESGGGLVQPGGSLRLSCAASGFSLSSSSMHWVRQAPGKGLEWVA
SISPYSGSTSYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCART
KYHYKNYYWWALDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAAL
GCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSS
LGTQTYICNVNHKPSNTKVDKKVEPKSC

3D structure

PDB

6xjw Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.

Chain

Resolution

1.918 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	S33 S55 Y57 S58 Y104 N108 Y109 Y110 W111	S31 S53 Y55 S56 Y102 N106 Y107 Y108 W109
BS02	rna	H	K103 H105 K107	K101 H103 K105

External links

PDB	RCSB:6xjw, PDBe:6xjw, PDBj:6xjw
PDBsum	6xjw
PubMed	35058645

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