Structure of PDB 6x5m Chain H

Receptor sequence

>6x5mH (length=225) Species: 10090 (Mus musculus) [Search protein sequence]

EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVAS
ISPYSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARQG
YRRRSGRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKKVEPKSC

3D structure

PDB

6x5m Dynamic bulge nucleotides in the KSHV PAN ENE triple helix provide a unique binding platform for small molecule ligands.

Chain

Resolution

2.5 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	Y34 P56 Y57 S58 S60 Q102 Y104 R105 R106 R110	Y31 P53 Y54 S55 S57 Q99 Y101 R102 R103 R107

External links

PDB	RCSB:6x5m, PDBe:6x5m, PDBj:6x5m
PDBsum	6x5m
PubMed	34871450

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