Structure of PDB 6wz5 Chain H

Receptor sequence
>6wz5H (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KRRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEA
SRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
3D structure
PDB6wz5 Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
ChainH
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H R27 K28 R30 K31 S33 I36 Y37 R3 K4 R6 K7 S9 I12 Y13
BS02 dna H T29 Y39 G50 I51 S52 S53 S84 T85 T5 Y15 G26 I27 S28 S29 S60 T61
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6wz5, PDBe:6wz5, PDBj:6wz5
PDBsum6wz5
PubMed32939087
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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