Structure of PDB 6ug8 Chain H

Receptor sequence

>6ug8H (length=213) Species: 10090 (Mus musculus) [Search protein sequence]

QVQLKESGPGLVAPSQSLSITCTVSGFSLNSYGVSWVRQPPGKGLEWLGV
IWGDGSTNYHSALMSRLRISKDNSKRQVFLKLNSLQTDDTATYYCTKPGS
GYAFAYWGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVT
VSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHK
PSNTKVDKKVEPA

3D structure

PDB

6ug8 The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody.

Chain

Resolution

1.89 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	GLA	H	G101 Y102	G101 Y102
BS02	GAL	H	W52 S56	W52 S56
BS03	SIA	H	S31 Y32 W52 G53 Y102	S31 Y32 W52 G53 Y102

External links

PDB	RCSB:6ug8, PDBe:6ug8, PDBj:6ug8
PDBsum	6ug8
PubMed	31831622

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