Structure of PDB 6u7a Chain H

Receptor sequence
>6u7aH (length=416) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
PQELAALHARHQQDYAALQGMKLALDLTRGKPSAEQLDLSNQLLSLPGDD
YRDPEGTDTRNYGGQHGLPGLRAIFAELLGIAVPNLIAGNNSSLELMHDI
VAFSMLYGGVDSPRPWIQEQDGIKFLCPVPGYDRHFAITETMGIEMIPIP
MLQDGPDVDLIEELVAVDPAIKGMWTVPVFGNPSGVTYSWETVRRLVQMR
TAAPDFRLFWDNAYAVHTLTLDFPRQVDVLGLAAKAGNPNRPYVFASTSK
ITFAGGGVSFFGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFFGDADGV
RLHMLRHQQILAPKFALVAEVLDQRLSESKIASWTEPKGGYFISLDVLPG
TARRTVALAKDVGIAVTEAGASFPYRKDPDDKNIRIAPSFPSVPDLRNAV
DGLATCALLAATETLL
3D structure
PDB6u7a Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis.
ChainH
Resolution2.22 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.6.1.1: aspartate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP H S100 L101 Y139 D218 A220 Y221 S254 S256 K257 S93 L94 Y132 D211 A213 Y214 S247 S249 K250
Gene Ontology
Molecular Function
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6u7a, PDBe:6u7a, PDBj:6u7a
PDBsum6u7a
PubMed32327655
UniProtO69689|ASPAT_MYCTU Aspartate aminotransferase (Gene Name=Rv3722c)

[Back to BioLiP]