Structure of PDB 6tbh Chain H

Receptor sequence
>6tbhH (length=534) Species: 498211 (Cellvibrio japonicus Ueda107) [Search protein sequence]
APLPELLSNNGKHALMVDGAPYIILGSQTNNSSNYPDALKDVWPSMEKMG
ANTLSIPVAWEQIEPVEGQFDFSFVDVLLKEARQRKVRLVLLWFATWKNN
APHYAPAWVKLDNARFPRVVKEDGDTLNSLSPLGQNTLAADKKAFVELMK
YLAKRDKDHTVIMVQVQNEVGTYGAVRDYSPMAQAVFNAAVPDDLIQKLQ
LKPGTWSQVFGRDADEFFHAYQIARYCDEVTVAGKAIKNLPMYVNVALRN
PFNPGLPGQYSSGGGTDNVLHIWKAAAPNIDLIAPDIYFRDYKTVSKVLE
LYTRPDNALFVAEIGNDQPFARYLFPTLGKGGIGFSPFGMDDTDYTNYPL
GAKVYNDETIEQFAQVYRLVNPMMREWARLSYQGQVWGVAEPLDSTTETQ
KITPEEKEQHKKDRASALTQQLDLGLWDAEVTYGRPMFWVTPPEGNTPAA
GGALIAQLDDNEYLVTAYKARVEFKPSQELAGKKFMIERVEEGRFEKGKW
VMERVWNGDQTDWGLNFTDRPHLLRVKMASYSVQ
3D structure
PDB6tbh Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine.
ChainH
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.23: beta-galactosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 N0K H N67 K134 N135 E205 Y324 F325 E349 F374 N383 L386 N31 K98 N99 E169 Y288 F289 E313 F338 N347 L350
Gene Ontology
Molecular Function
GO:0004565 beta-galactosidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0009341 beta-galactosidase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tbh, PDBe:6tbh, PDBj:6tbh
PDBsum6tbh
PubMed32899288
UniProtB3PBE0

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