Structure of PDB 6r6g Chain H

Receptor sequence

>6r6gH (length=190) Species: 9986 (Oryctolagus cuniculus)

MKTILSNQTVDIPENVDISLKGRTVIVKGPRGTLRRDFNHINVELSLLGK
KKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFP
INVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELVLEGND
IELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQA

3D structure

• PDB: 6r6g Structural and mutational analysis of the ribosome-arresting human XBP1u.
• Chain: H
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	M1 R23 H40 N42 V43 E44 K50 K53 R54 W60 R64 K65 A68 R71 T72 S75 H76 N79 H98 F99 G119 K121 Y122 E152 S155 N156 Q163 K168 K170 D171 R173 F175	M1 R23 H40 N42 V43 E44 K50 K53 R54 W60 R64 K65 A68 R71 T72 S75 H76 N79 H98 F99 G119 K121 Y122 E152 S155 N156 Q163 K168 K170 D171 R173 F175

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6r6g, PDBe:6r6g, PDBj:6r6g
• PDBsum: 6r6g
• PubMed: 31246176
• UniProt: G1SWI6|RL9_RABIT Large ribosomal subunit protein uL6 (Gene Name=RPL9)