Structure of PDB 6nnf Chain H

Receptor sequence

>6nnfH (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLQESGPGLVKPSETLSLTCTVSGGSISNYYWSWIRQSPGKGLEWIGY
ISDSESTNYNPSLKSRVIISVDTSKNQLSLKLNSVTAADSAIYYCARAQQ
GKRIYGMVSFGEFFYYYYMDVWGKGTTVTVSSASTKGPSVFPLAPSSGTA
ALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPS
SSLGTQTYICNVNHKPSNTKVDKKVEP

3D structure

PDB

6nnf Improvement of antibody functionality by structure-guided paratope engraftment.

Chain

Resolution

2.762 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	H	R100 Y100B	R103 Y105

External links

PDB	RCSB:6nnf, PDBe:6nnf, PDBj:6nnf
PDBsum	6nnf
PubMed	30760721

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