Structure of PDB 6mub Chain H

Receptor sequence

>6mubH (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVKAGGSLILSCGVSNFRISAHTMNWVRRVPGGGLEWVAS
ISTSSTYRDYADAVKGRFTVSRDDLEDFVYLQMHKMRVEDTAIYYCARKG
SDRLSDNDPFDAWGPGTVVTVSPASTKGPSVFPLAPSSKSTSGGTAALGC
LVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLG
TQTYICNVNHKPSNTKVDKKVEPKS

3D structure

PDB

6mub Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

Chain

Resolution

2.503 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	H	A31 D100B	A31 D106	PDBbind-CN: -logKd/Ki=7.00,Kd=0.1uM
BS02	MAN	H	T33 K95 D100B N100C D100D	T33 K99 D106 N107 D108	PDBbind-CN: -logKd/Ki=7.00,Kd=0.1uM

External links

PDB	RCSB:6mub, PDBe:6mub, PDBj:6mub
PDBsum	6mub
PubMed	16174734
UniProt	P0DOX5\|IGG1_HUMAN Immunoglobulin gamma-1 heavy chain

[Back to BioLiP]