Structure of PDB 6mu3 Chain H

Receptor sequence
>6mu3H (length=218) Species: 9606 (Homo sapiens) [Search protein sequence]
EVQLVESGGGLVKAGGSLILSCGVSNFRISAHTMNWVRRVPGGGLEWVAS
ISTSSTYRDYADAVKGRFTVSRDDLEDFVYLQMHKMRVEDTAIYYCARKG
SDRLSDNDPFDAWGPGTVVTVSPASTKGPSVFPLAPSGGTAALGCLVKDY
FPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYI
CNVNHKPSNTKVDKKVEP
3D structure
PDB6mu3 Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
ChainH
Resolution2.327 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN H A31 D100B A31 D106 PDBbind-CN: -logKd/Ki=6.15,Kd=0.7uM
BS02 MAN H A31 H32 T33 K95 G96 S100A D100B N100C D100D A31 H32 T33 K99 G100 S105 D106 N107 D108 PDBbind-CN: -logKd/Ki=6.15,Kd=0.7uM
External links
PDB RCSB:6mu3, PDBe:6mu3, PDBj:6mu3
PDBsum6mu3
PubMed16174734
UniProtP0DOX5|IGG1_HUMAN Immunoglobulin gamma-1 heavy chain

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