Structure of PDB 6mtj Chain H

Receptor sequence

>6mtjH (length=226) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLQESGPGLVKPSETLSLTCTVSGGSISNYYWSWIRQSPGKGLEWIGY
ISDSESTNYNPSLKSRVIISVDTSKNQLSLKLNSVTAADSAIYYCARAQQ
GKRIYGMVSFGEFFYYYYMDVWGKGTTVTVSSASTKGPSVFPLAPSGTAA
LGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSS
SLGTQTYICNVNHKPSNTKVDKKVEP

3D structure

PDB

6mtj Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.

Chain

Resolution

2.336 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	H	R100 Y100B	R103 Y105

External links

PDB	RCSB:6mtj, PDBe:6mtj, PDBj:6mtj
PDBsum	6mtj
PubMed	30604750

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