Structure of PDB 6msy Chain H

Receptor sequence

>6msyH (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVKAGGSLILSCGVSNFRISAHTMNWVRRVPGGGLEWVAS
ISTSSTYRDYADAVKGRFTVSRDDLEDFVYLQMHKMRVEDTAIYYCARKG
SDRLSDNDPFDAWGPGTVVTVSPASTKGPSVFPLAPGGTAALGCLVKDYF
PEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSQTYICNVNH
KPSNTKVDKKVEP

3D structure

PDB

6msy Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

Chain

Resolution

1.999 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	H	A31 H32 T33 K95 G96 S100A D100B N100C D100D	A31 H32 T33 K99 G100 S105 D106 N107 D108	PDBbind-CN: -logKd/Ki=7.00,Kd=0.1uM

External links

PDB	RCSB:6msy, PDBe:6msy, PDBj:6msy
PDBsum	6msy
PubMed	16174734
UniProt	P0DOX5\|IGG1_HUMAN Immunoglobulin gamma-1 heavy chain

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