Structure of PDB 6ifu Chain H

Receptor sequence

>6ifuH (length=341) Species: 767463 (Streptococcus thermophilus ND03) [Search protein sequence]

NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVE
KRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESN
SAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDF
GRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYS
AKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKD
YKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRM
KTKMVKKGVLKLTKAPLKTSLVKNHESFYEMGKANFMIKEI

3D structure

PDB

6ifu Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference

Chain

Resolution

3.05 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	G21 G23 S130 S131 K133 G134 A135 R137 T138 W169 Y177 D179 N182 D204 L215 G281 A282 G285 A286 K289 Y303 K307 K309 V315 K317	G19 G21 S124 S125 K127 G128 A129 R131 T132 W163 Y171 D173 N176 D198 L209 G275 A276 G279 A280 K283 Y297 K301 K303 V309 K311
BS02	rna	H	N69 A70 R74 W169 L215 P216 L217 K307	N67 A68 R72 W163 L209 P210 L211 K301

External links

PDB	RCSB:6ifu, PDBe:6ifu, PDBj:6ifu
PDBsum	6ifu
PubMed	30503210

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