Structure of PDB 6ifk Chain H

Receptor sequence

>6ifkH (length=345) Species: 767463 (Streptococcus thermophilus ND03) [Search protein sequence]

NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVE
KRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESD
KNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENA
VNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQK
WDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQA
FYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRR
YSRMKTKMVKKGVLKLTKAPLKTSLVKNHESFYEMGKANFMIKEI

3D structure

PDB

6ifk Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference

Chain

Resolution

3.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	G21 G23 S130 S131 K133 G134 R137 T138 W169 N182 K202 D204 L215 Y279 G281 A282 G283 G285 A286 T288 K289 Y303 M306 K307 K309 V315 K317	G19 G21 S128 S129 K131 G132 R135 T136 W167 N180 K200 D202 L213 Y277 G279 A280 G281 G283 A284 T286 K287 Y301 M304 K305 K307 V313 K315
BS02	rna	H	S28 N69 A70 N73 R74 W169 P216 L217 R305 K307	S26 N67 A68 N71 R72 W167 P214 L215 R303 K305

External links

PDB	RCSB:6ifk, PDBe:6ifk, PDBj:6ifk
PDBsum	6ifk
PubMed	30503210

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