Structure of PDB 6gk8 Chain H

Receptor sequence

>6gk8H (length=222) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLQQSGAEVKKPGESLKISCEASGYSFTNYWIGWVRQMPGKGLEWMGI
IYPGDSDTRYSPPFQGQVTITADRSITTAYLEWSSLKASDTAMYYCARVG
RPSKGGWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLV
KDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQ
TYICNVNHKPSNTKVDKRVEPK

3D structure

PDB

6gk8 A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.

Chain

Resolution

2.85 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	W33 Y52 D57 R59 R101 S103 K104 G105	W33 Y52 D57 R59 R101 S103 K104 G105

External links

PDB	RCSB:6gk8, PDBe:6gk8, PDBj:6gk8
PDBsum	6gk8
PubMed	29855358

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