Structure of PDB 6gk7 Chain H

Receptor sequence

>6gk7H (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVESGPEMRKPGESLKISCKTSGYIFSDYWTAWVRQLPGKGLQWMGI
IYSGDSDTRYHPSVQGHVTMSTDSSLTTAYLQWSSLKASDTGIYYCARLD
ARVDAGWQLDSWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKRVEPK

3D structure

PDB

6gk7 A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.

Chain

Resolution

2.95 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	W33 I50 Y52 D55 D57 R59 A101 W107	W33 I50 Y52 D55 D57 R59 A101 W107

External links

PDB	RCSB:6gk7, PDBe:6gk7, PDBj:6gk7
PDBsum	6gk7
PubMed	29855358

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