Structure of PDB 6gfe Chain H

Receptor sequence

>6gfeH (length=429) Species: 9606 (Homo sapiens) [Search protein sequence]

QVELQQSGPGLVKPSQTLSLTCAISGDSVSSRSASWSWIRQSPGRGLEWL
GRTYYRSHWYYEYAQSVKSRITINPDTSKNQFSLQLNSVTPEDTAVYYCA
RMDVPSFRYFDVWGQGTLVTVSSASTKGPSVFPLAPCSSESTAALGCLVK
DYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKT
YTCNVDHKPSNTKVDKRVESKGPSVFLFPPKPKDTLMISRTPEVTCVVVD
VSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLN
GKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSL
TCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKS
RWQEGNVFSCSVMHEALHNHYTQKSLSLS

3D structure

PDB

6gfe Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity.

Chain

Resolution

1.8 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BMA	H	F241 F243	F226 F228
BS02	CA	H	S33 D96	S33 D103

External links

PDB	RCSB:6gfe, PDBe:6gfe, PDBj:6gfe
PDBsum	6gfe
PubMed	31023536

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