Structure of PDB 6fi8 Chain H

Receptor sequence

>6fi8H (length=125) Species: 210 (Helicobacter pylori)

LYKSNHNVVYSCKYHIVWCPKYRRKVLVGAVEMRLKEIIQEVAKELRVEI
IEMQTDKDHIHILADIDPSFGVMKFIKTAKGRSSRILRQEFNHLKTKLPT
LWTNSCFISTVGGAPLNVVKQYIEN

3D structure

• PDB: 6fi8 Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering.
• Chain: H
• Resolution: 2.598 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	H	S9 N10 H11 N12 V14 L51 R52 D72 S74 F75	S4 N5 H6 N7 V9 L46 R47 D67 S69 F70
BS02	dna	H	K26 Y27 M78 K82 K85 G86 R87 S89 R90 R93 T105 L106 W107 T108 N109 S110 C111	K21 Y22 M73 K77 K80 G81 R82 S84 R85 R88 T100 L101 W102 T103 N104 S105 C106
BS03	dna	H	Y27 R28 Q59 H64 H66 P104	Y22 R23 Q54 H59 H61 P99
BS04	CA	H	Q126 E129	Q121 E124

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0004803 transposase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006313 DNA transposition

External links

• PDB: RCSB:6fi8, PDBe:6fi8, PDBj:6fi8
• PDBsum: 6fi8
• PubMed: 29635476
• UniProt: Q933Z0