Structure of PDB 6exn Chain H

Receptor sequence
>6exnH (length=411) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
IKFQRENWEMIRSHVSPIISNLTMDNLQESHRDLFQVNILIGRNIICKNV
VDFTLNNGRLIPALSALIALLNSDIPDIGETLAKELMLMFVQQFNRKDYV
SCGNILQCLSILFLYDVIHEIVILQILLLLLEKNSLRLVIAVMKICGWKL
ALVSKKTHDMIWEKLRYILQTQELSSTLRESLETLFEIRQKDYKSCENFN
ELTMAFDTLRQKLDVEFKKKIYLVLKSSLSGDEAAHKLLKLKIANNLKKS
VVDIIIKSSLQESTFSKFYSILSERMITFHRSWQTAYNETFEQNYTQDIE
DYETDQLRILGKFWGHLISYEFLPMDCLKIIKLTEEESCPQGRIFIKFLF
QELVNELGLDELQLRLNSSKLDGMFPLEGDAEHIRYSINFFTAIGLGLTE
DMRSRLTIIQE
3D structure
PDB6exn Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
ChainH
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna H K317 F354 H355 K242 F279 H280
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0005737 cytoplasm
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6exn, PDBe:6exn, PDBj:6exn
PDBsum6exn
PubMed29146871
UniProtP53333|CWC22_YEAST Pre-mRNA-splicing factor CWC22 (Gene Name=CWC22)

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