Structure of PDB 6db9 Chain H

Receptor sequence

>6db9H (length=219) Species: 32630 (synthetic construct) [Search protein sequence]

EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVAS
ISPYSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARQG
YRRRSGRGFDYWGQGTLVTVSSASTKGPSVFPLAPSGGTAALGCLVKDYF
PEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC
NVNHKPSNTKVDKKVEPKS

3D structure

PDB

6db9 Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.

Chain

Resolution

2.025 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	Y34 Y57 S58 S60 Q102 Y104 R105 R106 R110	Y31 Y54 S55 S57 Q99 Y101 R102 R103 R107	PDBbind-CN: Kd=708nM

External links

PDB	RCSB:6db9, PDBe:6db9, PDBj:6db9
PDBsum	6db9
PubMed	30382099

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