Structure of PDB 6crd Chain H

Receptor sequence
>6crdH (length=435) Species: 2280,384509 [Search protein sequence]
INETADDIVYRLTVIIDDRYESLKNLITLRADRLEMIINDNVSTILARDF
NNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYAL
SQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSC
HDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCH
NGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGE
RAEITCTCRDNWQGSNRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTV
GKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALT
DDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKE
DKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL
3D structure
PDB6crd Structure of an Influenza A virus N9 neuraminidase with a tetrabrachion-domain stalk.
ChainH
Resolution2.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BMA H P390 Q392 P356 Q358
BS02 MAN H R327 N329 D330 I366 I368 R294 N296 D297 I332 I334
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0046761 viral budding from plasma membrane
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6crd, PDBe:6crd, PDBj:6crd
PDBsum6crd
PubMed30713159
UniProtP03472|NRAM_I75A5 Neuraminidase (Gene Name=NA);
Q54436

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