Structure of PDB 6c8q Chain H

Receptor sequence
>6c8qH (length=267) Species: 226185 (Enterococcus faecalis V583) [Search protein sequence]
TTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGG
QDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAF
IQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVA
GENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELG
APEALYLKIPKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKK
GQHKRHLPITIFDDFWK
3D structure
PDB6c8q To be published
ChainH
Resolution2.583 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D53 E166
Catalytic site (residue number reindexed from 1) D52 E165
Enzyme Commision number 6.3.1.5: NAD(+) synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD H Y34 H38 G156 D181 Y33 H37 G155 D180
BS02 NAD H F133 N137 R141 F171 F172 T173 K174 H261 K262 F132 N136 R140 F170 F171 T172 K173 H253 K254
Gene Ontology
Molecular Function
GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0004359 glutaminase activity
GO:0005524 ATP binding
GO:0008795 NAD+ synthase activity
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0009435 NAD biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:6c8q, PDBe:6c8q, PDBj:6c8q
PDBsum6c8q
PubMed
UniProtQ830Y9|NADE_ENTFA NH(3)-dependent NAD(+) synthetase (Gene Name=nadE)

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