Structure of PDB 5z2l Chain H

Receptor sequence
>5z2lH (length=239) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
GAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQET
GATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGEALELNADDIDR
LFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKS
ALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIK
RHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGALEH
3D structure
PDB5z2l A potential substrate binding pocket of BdcA plays a critical role in NADPH recognition and biofilm dispersal
ChainH
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NDP H S15 R16 I18 Y37 A38 G39 S40 T58 D59 S60 N82 I130 S132 Y146 K150 I179 T181 N184 S14 R15 I17 Y36 A37 G38 S39 T57 D58 S59 N81 I129 S131 Y145 K149 I178 T180 N183 MOAD: Kd=45uM
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0035438 cyclic-di-GMP binding
GO:0042803 protein homodimerization activity
GO:0070402 NADPH binding
Biological Process
GO:0044010 single-species biofilm formation

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:5z2l, PDBe:5z2l, PDBj:5z2l
PDBsum5z2l
PubMed29462616
UniProtP39333|BDCA_ECOLI Cyclic-di-GMP-binding biofilm dispersal mediator protein (Gene Name=bdcA)

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