Structure of PDB 5pab Chain H

Receptor sequence
>5pabH (length=248) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYL
TGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
3D structure
PDB5pab Crystal Structure of a Factor VIIa complex
ChainH
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7XD H H41 C42 D44 K45 G85 S187 C188 K189 S192 S211 W212 G215 H41 C42 D44 K45 G85 S181 C182 K183 S186 S205 W206 G209 BindingDB: Ki=61.5nM
BS02 CA H E58 D60 E63 E68 E58 D60 E63 E68
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5pab, PDBe:5pab, PDBj:5pab
PDBsum5pab
PubMed
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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