Structure of PDB 5o32 Chain H

Receptor sequence
>5o32H (length=301) Species: 9606 (Homo sapiens) [Search protein sequence]
EDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVC
ATNRRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEG
IVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLS
INSTECLHVHCRGLETSLAECTFTKRRTMGYQDFADVVCYTQKADSPMDD
FFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQ
YQCNGEVDCITGEDEVGCAGEETEILTADMDAERRRIKSLLPKLSCGVKN
R
3D structure
PDB5o32 Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
ChainH
Resolution4.20621 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.45: complement factor I.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA H Y276 N279 E281 D283 D289 E290 Y251 N254 E256 D258 D264 E265
BS02 CA H K239 A240 D242 I244 D246 D252 E253 K214 A215 D217 I219 D221 D227 E228
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5o32, PDBe:5o32, PDBj:5o32
PDBsum5o32
PubMed28671664
UniProtP05156|CFAI_HUMAN Complement factor I (Gene Name=CFI)

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