Structure of PDB 5ijz Chain H

Receptor sequence
>5ijzH (length=447) Species: 196627 (Corynebacterium glutamicum ATCC 13032) [Search protein sequence]
MTVDEQVSNYYDMLLKRNAGEPEFHQAVAEVLESLKIVLEKDPHYADYGL
IQRLCEPERQLIFRVPWVDDQGQVHVNRGFRVQFNSALGPYKGGLRFHPS
VNLGIVKFLGFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDLEIMRFCQSF
MTELHRHIGEYRDVPAGDIGVGGREIGYLFGHYRRMANQHESGVLTGKGL
TWGGSLVRTEATGYGCVYFVSEMIKAKGESISGQKIIVSGSGNVATYAIE
KAQELGATVIGFSDSSGWVHTPNGVDVAKLREIKEVRRARVSVYADEVEG
ATYHTDGSIWDLKCDIALPCATQNELNGENAKTLADNGCRFVAEGANMPS
TPEAVEVFRERDIRFGPGKAANAGGVATSALEMQQNASRDSWSFEYTDER
LQVIMKNIFKTCAETAAEYGHENDYVVGANIAGFKKVADAMLAQGVI
3D structure
PDB5ijz Structural insights into domain movement and cofactor specificity of glutamate dehydrogenase from Corynebacterium glutamicum
ChainH
Resolution2.29 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K128 D168
Catalytic site (residue number reindexed from 1) K128 D168
Enzyme Commision number 1.4.1.4: glutamate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP H R96 K136 D168 I169 R208 T212 S241 G242 N243 V244 D264 S265 R290 A321 T322 A346 N347 N372 R96 K136 D168 I169 R208 T212 S241 G242 N243 V244 D264 S265 R290 A321 T322 A346 N347 N372
BS02 AKG H K92 G94 Q113 K116 K128 A166 S379 K92 G94 Q113 K116 K128 A166 S379
Gene Ontology
Molecular Function
GO:0004353 glutamate dehydrogenase [NAD(P)+] activity
GO:0004354 glutamate dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
Biological Process
GO:0006520 amino acid metabolic process
GO:0006537 glutamate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ijz, PDBe:5ijz, PDBj:5ijz
PDBsum5ijz
PubMed25727019
UniProtP31026|DHE4_CORGL NADP-specific glutamate dehydrogenase (Gene Name=gdh)

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