Structure of PDB 5ghw Chain H

Receptor sequence

>5ghwH (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVKPGGSLRLSCSASGFDFDNAWMTWVRQPPGKGLEWVGR
ITGPGEGWSVDYAAPVEGRFTISRLNSINFLYLEMNNLRMEDSGLYFCAR
TGKYYDFWSGYPPGEEYFQDWGRGTLVTVSSASTKGPSVFPLAPSSKSTS
GGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVV
TVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS

3D structure

PDB

5ghw Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface

Chain

Resolution

2.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	W33 G52C E53 K97 Y98 Y99 F100A W100B G100D Y100E P100F P100G	W33 G55 E56 K103 Y104 Y105 F107 W108 G110 Y111 P112 P113

External links

PDB	RCSB:5ghw, PDBe:5ghw, PDBj:5ghw
PDBsum	5ghw
PubMed	27905530

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