Structure of PDB 5g6s Chain H

Receptor sequence
>5g6sH (length=289) Species: 5062 (Aspergillus oryzae) [Search protein sequence]
SKHIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLAST
ISEGVNANDLIIICLLNNQVVEDALRDALQTLPSKTIVNLTNGTPNQARK
LADFVTSHGARYIHGGIMAVPTMIGSPHAVLLYSGESLELFQSIESHLSL
LGMSKYLGTDAGSASLHDLALLSGMYGLFSGFLHAVALIKSGQDTSTTAT
GLLPLLTPWLSAMTGYLSSIAKQIDDGDYATQGSNLGMQLAGVENIIRAG
EEQRVSSQMILPIKALIEQAVGEGHGGEDLSALIEYFKV
3D structure
PDB5g6s A reductive aminase from Aspergillus oryzae.
ChainH
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP H N236 M239 N235 M238
BS02 RAU H M214 S235 M239 Q240 G243 M213 S234 M238 Q239 G242
BS03 NDP H G11 A12 M13 N32 R33 T34 K37 C65 L66 L67 V71 N93 I118 A120 P122 G10 A11 M12 N31 R32 T33 K36 C64 L65 L66 V70 N92 I117 A119 P121
BS04 RAU H V121 M176 Y177 F180 V120 M175 Y176 F179
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding

View graph for
Molecular Function
External links
PDB RCSB:5g6s, PDBe:5g6s, PDBj:5g6s
PDBsum5g6s
PubMed28937665
UniProtQ2TW47|REDAM_ASPOR NADPH-dependent reductive aminase (Gene Name=AO090010000708)

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