Structure of PDB 5alc Chain H

Receptor sequence
>5alcH (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]
VQLQESGAEVKKPGSSVRVSCKASGGTFDSYSIHWVRQAPGQGLEWMGGI
IPAFGTLSSAQDFQARVTISADKSTSTAYMELSGLRSEDTAVYYCARGSH
LYPNDALAIWGQGTLVTVSSASTKGPSVFPLAPSSKSTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICN
VNHKPSNTKVDKRVEP
3D structure
PDB5alc Structural and Functional Characterisation of a Specific Antidote for Ticagrelor.
ChainH
Resolution1.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TIQ H H35 W47 I52 L57 Y99 D100J L100L H34 W46 I51 L57 Y102 D105 L107 PDBbind-CN: -logKd/Ki=8.13,Kd=7.4nM
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