Structure of PDB 4uin Chain H

Receptor sequence
>4uinH (length=221) Species: 10090 (Mus musculus) [Search protein sequence]
EVQLQQSGTVLARPGASVKMSCEASGYTFTSYWMHWLKKRPGQGLEWIGT
IYPGNSDSSYNQRFKGKAKLTAVTSTSTAYMELSSLTNEDSAVYYCTRER
GLYYGGRSFDYWGQGTTLTVSSAKTTPPSVYPLAPGSNSMVTLGCLVKGY
FPEPVTVTWNSGSLSSGVHTFPAVLESDLYTLSSSVTVPSSPRPSETVTC
NVAHPASSTKVDKKIVPRDCG
3D structure
PDB4uin Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3
ChainH
Resolution2.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QI9 H W33 T50 E99 G106 R107 F109 W33 T50 E99 G106 R107 F109 MOAD: Kd=24nM
PDBbind-CN: -logKd/Ki=7.62,Kd=24nM
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