Structure of PDB 4qyz Chain H

Receptor sequence
>4qyzH (length=359) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRK
SGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSV
DEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAI
RVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWF
TAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEI
ATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKA
KDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDITAQVKQMPTLEQL
KSWVRNNGE
3D structure
PDB4qyz Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target.
ChainH
Resolution3.0303 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna H R20 D21 D22 K27 S40 Q42 S43 R46 R49 M166 F200 T201 V203 A265 K266 R20 D21 D22 K27 S40 Q42 S43 R46 R49 M166 F200 T201 V203 A265 K266
BS02 dna H D109 A110 T168 G210 S211 H213 L214 D109 A110 T168 G210 S211 H213 L214
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4qyz, PDBe:4qyz, PDBj:4qyz
PDBsum4qyz
PubMed25123481
UniProtQ46899|CASC_ECOLI CRISPR system Cascade subunit CasC (Gene Name=casC)

[Back to BioLiP]