Structure of PDB 4onf Chain H

Receptor sequence

>4onfH (length=212) Species: 10090 (Mus musculus) [Search protein sequence]

EVKLVESGGGLVKPGASLKLSCAASGFTFSNYGMSWVRQNSDKRLEWVAS
IRSGGGRTYYSDNVKGRFTISRENAKNTLYLQMSSLKSEDTALYYCVRYD
HYSGSSDYWGQGTTVTVSSAKTTPPSVYPLAPSMVTLGCLVKGYFPEPVT
VTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPA
SSTKVDKKIVPR

3D structure

PDB

4onf Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab.

Chain

Resolution

2.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	G33 S50 R52 Y59 Y99 S105 S106	G33 S50 R52 Y59 Y99 S105 S106

External links

PDB	RCSB:4onf, PDBe:4onf, PDBj:4onf
PDBsum	4onf
PubMed	25024748

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