Structure of PDB 4obu Chain H

Receptor sequence
>4obuH (length=462) Species: 411470 (Mediterraneibacter gnavus ATCC 29149) [Search protein sequence]
TEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKI
PEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTS
AYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANIT
ALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTN
SHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCK
KHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCA
MVLVKDIRNLFHSFHVNPEYLDIGMELTRPARGLKLWLTLQVLGSDLIGS
AIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDIL
NEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQ
YGREIYTEMKKA
3D structure
PDB4obu Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine.
ChainH
Resolution2.804 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.1.1.105: L-tryptophan decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP H F98 G159 S160 H192 T249 D274 A276 K306 Y312 F83 G144 S145 H177 T234 D259 A261 K291 Y297
Gene Ontology
Molecular Function
GO:0004058 aromatic-L-amino-acid decarboxylase activity
GO:0016830 carbon-carbon lyase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0036469 L-tryptophan decarboxylase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006568 tryptophan metabolic process
GO:0019752 carboxylic acid metabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4obu, PDBe:4obu, PDBj:4obu
PDBsum4obu
PubMed25263219
UniProtA7B1V0|TRPDC_MEDG7 Tryptophan decarboxylase (Gene Name=RUMGNA_01526)

[Back to BioLiP]