Structure of PDB 4nrx Chain H

Receptor sequence

>4nrxH (length=231) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGAEVKKPGESLKISCKVSGYNFASEWIGWVRQMPGKGLEWMGI
IYPGDSDTKYSPSFQGQVIISADKSINTAYLQWSSLKASDTAIYYCARQN
HYGSGSYFYRTAYYYAMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSG
GTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVT
VPSSSLGTQTYICNVNHKPSNTKVDKKVEPK

3D structure

PDB

4nrx Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6.

Chain

Resolution

2.21 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	S31 W33 Y52 D54 D56 K58 H97 Y100C R100F T100G A100H Y100I Y100K	S31 W33 Y52 D55 D57 K59 H101 Y107 R110 T111 A112 Y113 Y115

External links

PDB	RCSB:4nrx, PDBe:4nrx, PDBj:4nrx
PDBsum	4nrx
PubMed	24335316

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