Structure of PDB 4nhc Chain H

Receptor sequence

>4nhcH (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGAEVKRPGSSVTVSCKASGGSFSTYALSWVRQAPGRGLEWMGG
VIPLLTITNYAPRFQGRITITADRSTSTAYLELNSLRPEDTAVYYCAREG
TTGWGWLGKPIGAFAHWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTA
ALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPS
SSLGTQTYICNVNHKPSNTKVDKKVEPK

3D structure

PDB

4nhc Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.

Chain

Resolution

2.912 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	A33 G50 V51 I52 N58 E95 G100D K100E P100F	A33 G50 V51 I52 N59 E99 G108 K109 P110
BS02	TFA	H	Q39 A40 P41 G42	Q39 A40 P41 G42

External links

PDB	RCSB:4nhc, PDBe:4nhc, PDBj:4nhc
PDBsum	4nhc
PubMed	25420104

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